[Prospec] Product
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Prospec의 CD Antigens 제품을 소개드립니다.
[Prospec] CD207 Human
Product Information:
Catalogue number:
PRO-2204
Introduction:
CD207 (C-type lectin domain family 4 member K) is expressed in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. Moreover, CD207 is expressed in several other dendritic cell types including dermal CD103+ DCs and splenic CD8+ DCs. Langerin is localized in the Birbeck granules, the organelles present in the cytoplasm of Langerhans cells and comprised of superimposed and zippered membranes.
CD207 is a C-type lectin with mannose binding specificity, and it has been suggested that mannose binding by the CD207 protein leads to internalization of antigen into Birbeck granules thus providing access to a nonclassical antigen-processing pathway.
Description:
- CD207 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 287 amino acids (65-328 a.a) and having a molecular mass of 32.2kDa.
- CD207 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source:
Escherichia Coli.
Physical Appearance:
Sterile Filtered clear solution.
Formulation:
CD207 protein solution (1mg/ml) containing 20mM Tris 8.0 and 10% glycerol.
Stability:
- Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
- For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
- Avoid multiple freeze-thaw cycles.
Purity:
Greater than 85.0% as determined by SDS-PAGE.
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